Human on a Chip - Emulate
On this episode we’ll meet Dr. Daniel Levner, co-founder and Chief Technology Officer at Emulate, a company commercializing technology to remake human biology from the ground up using small rubbery microfluidic chips.
Forged in a multi-year partnership between DARPA and Harvard’s Wyss Institute for Biologically Inspired Engineering, Emulate develops organ chips for the lung, intestine, liver, kidney, and even the brain. Slotting in between cell culture dishes, organoids, and animal models, this burgeoning area is one in which startups must marry high design and fundamentally challenging biomedical engineering to recapitulate a human being on a chip reproducibly, at scale, and under budget. Their challenge, to simultaneously accelerate and improve outcomes while reducing costs in drug development, is immense. In response, Emulate’s organ chips are elegantly engineered works of art that could enable scientists to move beyond the dish and blur the lines between in vitro and in vivo.
This is the TomorrowScale podcast. Hosted by Justin Briggs.
“Reconstituting Organ-Level Lung Functions on a Chip” (Huh et al 2010)
Axial’s Joshua Elkington recently published a primer on Emulate
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The TomorrowScale Podcast was created to showcase scientists and entrepreneurs who are building science-based businesses, and to hear stories from the benches and in the trenches of research & development. The views expressed by the host and guests are their own, and the content of this show should not be considered legal, tax, or investing advice. Thanks to our guests for sharing their time and knowledge with us. Thank you for listening. Please science responsibly.